Open AccessA Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects
Author(s) -
Senthilkumar Sadhasivam,
Blessed W Aruldhas,
Senthil Packiasabapathy,
Brian R. Overholser,
Pengyue Zhang,
Yong Zang,
Janelle S Renschler,
Ryan Fitzgerald,
Sara K. Quinney
Publication year - 2021
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000005366
Subject(s) - medicine , methadone , anesthesia , analgesic , interquartile range , opioid , adverse effect , perioperative , vomiting , rocuronium , population , dosing , remifentanil , surgery , propofol , receptor , environmental health