Open AccessAssociation Between Behavioral and Learning Outcomes and Single Exposures to Procedures Requiring General Anesthesia Before Age 3: Secondary Analysis of Data From Olmsted County, MN
Author(s) -
David O. Warner,
Dayu Hu,
Michael J. Zaccariello,
Darrell R. Schroeder,
Andrew C. Hanson,
Robert T. Wilder,
Juraj Šprung,
Randall P. Flick
Publication year - 2020
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000005180
Subject(s) - medicine , confidence interval , retrospective cohort study , attention deficit hyperactivity disorder , pediatrics , cohort , population , cohort study , incidence (geometry) , cumulative incidence , anesthesia , psychiatry , surgery , physics , environmental health , optics
Two prior population-based (children born in Olmsted County, MN), retrospective cohort studies both found that multiple exposures to anesthesia before age 3 were associated with a significant increase in the frequency of attention-deficit hyperactivity disorder (ADHD) and learning disabilities (LD) later in life. The primary purpose of this secondary analysis of these data was to test the hypothesis that a single exposure to anesthesia before age 3 was associated with an increased risk of ADHD. We also examined the association of single exposures with LD and the need for individualized educational plans as secondary outcomes.