Open AccessAcute Postoperative Pain Is Associated With Myocardial Injury After Noncardiac Surgery
Author(s) -
Alparslan Turan,
Steve Leung,
Gausan Ratna Bajracharya,
Rovnat Babazade,
Theresa Barnes,
Yehoshua N Schacham,
Guangmei Mao,
Nicole M. Zimmerman,
Kurt Ruetzler,
Kamal Maheshwari,
Wael Ali Sakr Esa,
Daniel I. Sessler
Publication year - 2020
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000005033
Subject(s) - medicine , hazard ratio , confidence interval , anesthesia , confounding , troponin , retrospective cohort study , cardiology , myocardial infarction
Uncontrolled pain after noncardiac surgery activates the sympathetic nervous system, which causes tachycardia, hypertension, and increased cardiac contractility-all of which may increase myocardial oxygen demand. We therefore determined whether time-weighted average pain scores over the initial 72 postoperative hours are associated with myocardial injury after noncardiac surgery (MINS).