Open AccessReal-Time Intraoperative Determination and Reporting of Cerebral Autoregulation State Using Near-Infrared Spectroscopy
Author(s) -
Dean Montgomery,
Charles H. Brown,
Charles W. Hogue,
Ken Brady,
Mitsunori Nakano,
Yohei Nomura,
Artur Antunes,
Paul Addison
Publication year - 2019
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000004614
Subject(s) - cerebral autoregulation , autoregulation , transcranial doppler , cerebral blood flow , anesthesia , blood pressure , medicine , near infrared spectroscopy , cardiopulmonary bypass , hemodynamics , chemistry , cardiology , psychology , neuroscience
Cerebral blood flow (CBF) is maintained over a range of blood pressures through cerebral autoregulation (CA). Blood pressure outside the range of CA, or impaired autoregulation, is associated with adverse patient outcomes. Regional oxygen saturation (rSO2) derived from near-infrared spectroscopy (NIRS) can be used as a surrogate CBF for determining CA, but existing methods require a long period of time to calculate CA metrics. We have developed a novel method to determine CA using cotrending of mean arterial pressure (MAP) with rSO2that aims to provide an indication of CA state within 1 minute. We sought to determine the performance of the cotrending method by comparing its CA metrics to data derived from transcranial Doppler (TCD) methods.