Open AccessAnesthesia With and Without Nitrous Oxide and Long-term Cognitive Trajectories in Older Adults
Author(s) -
Juraj Šprung,
Arnoley S. Abcejo,
David S. Knopman,
Ronald C. Petersen,
Michelle M. Mielke,
Andrew C. Hanson,
Darrell R. Schroeder,
Phillip J. Schulte,
David P. Martin,
Toby N. Weingarten,
Jeffrey J. Pasternak,
David O. Warner
Publication year - 2019
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000004490
Subject(s) - medicine , interquartile range , confidence interval , cognition , nitrous oxide , anesthesia , postoperative cognitive dysfunction , population , surgery , psychiatry , environmental health
We evaluated the hypothesis that the rate of postoperative decline in global cognition is greater in older adults exposed to general anesthesia with nitrous oxide (N2O) compared to general anesthesia without N2O.