Open AccessEffect of Sugammadex on Postoperative Myasthenic Crisis in Myasthenia Gravis Patients: Propensity Score Analysis of a Japanese Nationwide Database
Author(s) -
Hisatsugu Mouri,
Taisuke Jo,
Hiroki Matsui,
Kiyohide Fushimi,
Hideo Yasunaga
Publication year - 2020
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000004239
Subject(s) - medicine , sugammadex , myasthenia gravis , thymectomy , odds ratio , body mass index , anesthesia , rocuronium , propensity score matching , confidence interval , mechanical ventilation , comorbidity , surgery , intubation
In myasthenia gravis (MG) patients, postoperative myasthenic crisis, and residual neuromuscular blocking agent (NMBA) can cause respiratory failure that requires mechanical ventilation. However, it remains unclear whether the use of sugammadex for NMBA reversal reduces postoperative myasthenic crisis in MG patients undergoing surgery. We analyzed the association between use of sugammadex and postoperative myasthenic crisis in patients with MG using a national inpatient database.