Open AccessAssociation of Intraoperative Ventilator Management With Postoperative Oxygenation, Pulmonary Complications, and Mortality
Author(s) -
Nicholas J. Douville,
Elizabeth S. Jewell,
Neal Duggal,
Ross Blank,
Sachin Kheterpal,
Milo Engoren,
Michael R. Mathis
Publication year - 2020
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000004191
Subject(s) - medicine , interquartile range , anesthesia , odds ratio , mechanical ventilation , oxygenation , plateau pressure , positive end expiratory pressure , ventilation (architecture) , surgery , cardiology , tidal volume , respiratory system , mechanical engineering , engineering
"Lung-protective ventilation" describes a ventilation strategy involving low tidal volumes (VTs) and/or low driving pressure/plateau pressure and has been associated with improved outcomes after mechanical ventilation. We evaluated the association between intraoperative ventilation parameters (including positive end-expiratory pressure [PEEP], driving pressure, and VT) and 3 postoperative outcomes: (1) PaO2/fractional inspired oxygen tension (FIO2), (2) postoperative pulmonary complications, and (3) 30-day mortality.