Open AccessInvasive Respiratory or Vasopressor Support and/or Death as a Proposed Composite Outcome Measure for Perioperative Care Research
Author(s) -
Toshiyuki Mizota,
Dong Li,
Chikashi Takeda,
Atsuko Shiraki,
Shino Matsukawa,
Satoshi Shimizu,
Shinichi Kai
Publication year - 2019
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000003921
Subject(s) - medicine , perioperative , hazard ratio , confidence interval , proportional hazards model , mechanical ventilation , retrospective cohort study , abdominal surgery , surgery
There is a need for a clinically relevant and feasible outcome measure to facilitate clinical studies in perioperative care medicine. This large-scale retrospective cohort study proposed a novel composite outcome measure comprising invasive respiratory or vasopressor support (IRVS) and death. We described the prevalence of IRVS in patients undergoing major abdominal surgery and assessed the validity of combining IRVS and death to form a composite outcome measure.