Open AccessReversing Cholinergic Bronchoconstriction by Common Inotropic Agents: A Randomized Experimental Trial on Isolated Perfused Rat Lungs
Author(s) -
Gergely H. Fodor,
Sam Bayat,
Barna Babik,
Walid Habre,
Ferenc Peták
Publication year - 2019
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000003502
Subject(s) - milrinone , dobutamine , bronchoconstriction , inotrope , levosimendan , saline , anesthesia , medicine , perfusion , lung , vasodilation , hemodynamics , airway
The ability of inotropic agents to alter airway reactivity and lung tissue mechanics has not been compared in a well-controlled experimental model. Therefore, we compared the potential to alter lung tissue viscoelasticity and bronchodilator effects of commonly used inotropic agents in an isolated perfused rat lung model.