Open AccessMixing Studies in Patients With Prolonged Activated Partial Thromboplastin Time or Prothrombin Time
Author(s) -
Honorio T. Benzon,
Meghan Park,
Robert J. McCarthy,
Mark C. Kendall,
Paul F. Lindholm
Publication year - 2019
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000003457
Subject(s) - partial thromboplastin time , prothrombin time , lupus anticoagulant , medicine , coagulation testing , gastroenterology , thromboplastin , anticoagulant , clotting time , coagulation , anesthesia , thrombosis
Patients presenting for surgery may have isolated or combined prolonged activated partial thromboplastin time (aPTT) and/or prothrombin time (PT). In patients not receiving anticoagulants or with no identifiable cause for abnormal clot formation, a mixing study is performed. The index of circulating anticoagulant (ICA) has been used to predict the presence of an inhibitor, usually a lupus anticoagulant.