Open AccessCerebral Small Vessel, But Not Large Vessel Disease, Is Associated With Impaired Cerebral Autoregulation During Cardiopulmonary Bypass: A Retrospective Cohort Study
Author(s) -
Yohei Nomura,
Roland Faegle,
Daijiro Hori,
Abbas AlQamari,
Alexander J. Nemeth,
Rebecca F. Gottesman,
Gayane Yenokyan,
Charles H. Brown,
Charles W. Hogue
Publication year - 2018
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000003384
Subject(s) - medicine , cerebral autoregulation , transcranial doppler , cardiology , cardiopulmonary bypass , cerebral blood flow , stenosis , anesthesia , autoregulation , blood pressure
Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery. We hypothesize that large and/or small vessel cerebral arterial disease is associated with impaired cerebral autoregulation during CPB.