Open AccessRandomized Clinical Trial of Preoperative High-Dose Methylprednisolone on Postoperative Pain at Rest After Laparoscopic Appendectomy
Author(s) -
Jakob Kleif,
Camilla Ibsen Hauge,
Jesper Vilandt,
Ismail Gögenur
Publication year - 2018
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000002693
Subject(s) - medicine , methylprednisolone , placebo , anesthesia , randomized controlled trial , surgery , analgesic , nausea , methylprednisolone acetate , appendicitis , alternative medicine , pathology
Methylprednisolone administered intravenously preoperatively has been shown to reduce pain, nausea, and fatigue after elective surgery. We aimed to show that 125 mg of methylprednisolone given intravenously 30 minutes before laparoscopic surgery for suspected appendicitis would reduce pain at rest during the first 3 postoperative days.