Open AccessReduced Left Ventricular Global Longitudinal Strain Predicts Prolonged Hospitalization: A Cohort Analysis of Patients Having Aortic Valve Replacement Surgery
Author(s) -
Abraham Sonny,
Andrej Alfirevic,
Shiva Sale,
Nicole M. Zimmerman,
Jing You,
A. Marc Gillinov,
Daniel I. Sessler,
Andra E. Duncan
Publication year - 2018
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000002684
Subject(s) - medicine , cardiology , ejection fraction , aortic valve replacement , speckle tracking echocardiography , aortic valve stenosis , odds ratio , stenosis , confidence interval , sinus rhythm , atrial fibrillation , heart failure
Left ventricular ejection fraction (LVEF) is often preserved in patients with aortic stenosis and thus cannot distinguish between normal myocardial contractile function and subclinical dysfunction. Global longitudinal strain and strain rate (SR), which measure myocardial deformation, are robust indicators of myocardial function and can detect subtle myocardial dysfunction that is not apparent with conventional echocardiographic measures. Strain and SR may better predict postoperative outcomes than LVEF. The primary aim of our investigation was to assess the association between global longitudinal strain and serious postoperative outcomes in patients with aortic stenosis having aortic valve replacement. Secondarily, we also assessed the associations between global longitudinal SR and LVEF and the outcomes.