Open AccessComparison of Transcranial Doppler and Ultrasound-Tagged Near Infrared Spectroscopy for Measuring Relative Changes in Cerebral Blood Flow in Human Subjects
Author(s) -
Michael S Lipnick,
Elizabeth A Cahill,
John Feiner,
Philip E. Bickler
Publication year - 2018
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000002590
Subject(s) - medicine , hypocapnia , cerebral blood flow , transcranial doppler , middle cerebral artery , hyperventilation , hypercapnia , anesthesia , blood flow , neurointensive care , cardiology , ischemia , acidosis
Currently, no reliable method exists for continuous, noninvasive measurements of absolute cerebral blood flow (CBF). We sought to determine how changes measured by ultrasound-tagged near-infrared spectroscopy (UT-NIRS) compare with changes in CBF as measured by transcranial Doppler (TCD) in healthy volunteers during profound hypocapnia and hypercapnia.