Open AccessOutcomes in Patients Undergoing Cardiac Surgery Who Decline Transfusion and Received Erythropoietin Compared to Patients Who Did Not: A Matched Cohort Study
Author(s) -
Lorent Duce,
Mary Cooter,
Sharon L. McCartney,
Frederick W. Lombard,
Nicole R. Guinn
Publication year - 2018
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000002418
Subject(s) - medicine , erythropoietin , perioperative , euroscore , blood management , anemia , blood transfusion , intensive care unit , cardiac surgery , atrial fibrillation , cohort , retrospective cohort study , surgery
Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood transfusion who received EPO with a matched cohort who did not.