Open AccessFeasibility of Automated Propofol Sedation for Transcatheter Aortic Valve Implantation: A Pilot Study
Author(s) -
Cédrick Zaouter,
Thomas M. Hemmerling,
Stéfano Mion,
Lionel Leroux,
Alain Rémy,
Alexandre Ouattara
Publication year - 2017
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000001737
Subject(s) - sedation , medicine , bispectral index , propofol , anesthesia , hemodynamics , surgery
Recently, several trials have shown that closed-loop sedation is feasible. No study has used automated sedation in extremely frail patients, such as those scheduled for transcatheter aortic valve implantation (TAVI). We developed and tested a novel automated sedation system for this kind of population and surgery. The system integrates a decision support system that detects respiratory and hemodynamic events via smart alarms, which provide pertinent/related clinical suggestions and treatment options. The main objective was the feasibility of closed-loop sedation, defined as successful automated sedation without manual override. Secondary qualitative observations were clinical and controller performance.