Open AccessHypergravity Exposure for 14 Days Increases the Effects of Propofol in Rats
Author(s) -
Chuzo Iwata,
Chikara Abe,
Mitsuhiro Nakamura,
Hironobu Morita
Publication year - 2014
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000000041
Subject(s) - propofol , hypergravity , medicine , anesthesia , vestibular system , nadir , anesthetic , blood pressure , audiology , satellite , engineering , aerospace engineering
It is thought that the gravitational environment of space exploration alters the effects of anesthetics; however, no evidence has as yet been reported. In the present study, we sought to provide direct evidence showing that hypergravity exposure for 14 days increases anesthetic effects and to examine the possible causes.