Open AccessLocal Anesthetic Switching for Intrathecal Tachyphylaxis in Cancer Patients with Pain
Author(s) -
Sebastiano Mercadante,
Patrizia Villari,
Patrizia Ferrera,
Edoardo Arcuri
Publication year - 2003
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/01.ane.0000067403.15926.bd
Subject(s) - medicine , tachyphylaxis , intrathecal , anesthesia , anesthetic , local anesthetic , cancer pain , cancer , pharmacology
Switching from bupivacaine to lidocaine may improve intrathecal morphine analgesia in advanced cancer patients, possibly because of different spinal mechanisms limiting the hyperalgesic processes.