
Do Volatile Anesthetics Act as Ideal Gases?
Author(s) -
E. I. Eger,
Brynte H. Johnson
Publication year - 1979
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/00000539-197907000-00013
Subject(s) - enflurane , isoflurane , halothane , medicine , volatile anesthetic , anesthetic , anesthesia , vapor phase , ideal (ethics) , vapor pressure , nitrous oxide , thermodynamics , philosophy , physics , epistemology
Under conditions of temperature and pressure commonly found in operating rooms, the anesthetics enflurane, halothane, and isoflurane act as nearly ideal gasses even at concentrations producing a saturated vapor phase. The deviations from ideality are 3.44 +/- 0.44% (SEM) for enflurane, 0.94 +/- 0.30% for halothane, and 2.96 +/- 0.29% for isoflurane. That is, 0.9 to 3.4% more anesthetic is vaporized than would be predicted from the vapor pressure of these agents.