Open AccessThe Effect of Spontaneous Versus Controlled Ventilation on the Rate of Rise of Alveolar Halothane Concentration in Dogs
Author(s) -
Robert T. Gibbons,
Eugene Steffey,
Edmond I. Eger
Publication year - 1977
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/00000539-197701000-00010
Subject(s) - medicine , halothane , anesthesia , ventilation (architecture) , engineering , mechanical engineering
The rate of rise of the alveolar:inspired halothane concentration (F delta/F1) ratio was measured in dogs breathing spontaneously. These rates were measured at inspired concentrations of 0.3, 1.5, and 4 percent. Initially, FON (FA/F1) ratio was measured in dogs breathing spontaneously. These rates were measured at inspired concentrations of 0.3, 1.5, and 4 percent. Initially FA/F1 rose at similar rates for all 3 concentrations, but a 4 percent, the plateau attained was lower as a result of respiratory depression. In a 2nd group of dogs, FA/FI was measured for inspired concentrations of 0.3, 1.5, 4, and 6 percent during controlled ventilation. FA/FI rose at similar rates at the lower 2 concentrations but at progressively more rapid rates at inspired concentrations of 4 and 6 percent, presumably as a result of circulatory depression.