Open AccessConnectomic Profiles and Cognitive Trajectories After Epilepsy Surgery in Children
Author(s) -
Olivia N Arski,
Daniel J. Martire,
Julia M. Young,
Simeon M. Wong,
Hrishikesh Suresh,
Elizabeth Kerr,
Ayako Ochi,
Hiroshi Otsubo,
Roy Sharma,
Elysa Widjaja,
Carter Snead,
Elizabeth Donner,
Mary Lou Smith,
George M. Ibrahim
Publication year - 2022
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000200273
Subject(s) - epilepsy , cognition , epilepsy surgery , medicine , psychology , neuroscience , physical medicine and rehabilitation
Neurocognitive outcomes after surgery for temporal lobe epilepsy in childhood are variable. Postoperative changes are not directly predicted by seizure freedom, and associations between epilepsy, neuropsychological function, and developing neural networks are poorly understood. Here, we leveraged whole-brain connectomic profiling in magnetoencephalography (MEG) to retrospectively study associations between brain connectivity and neuropsychological function in children with temporal lobe epilepsy undergoing resective surgery.