Open AccessMicroRNAs as Biomarkers of Charcot-Marie-Tooth Disease Type 1A
Author(s) -
Hongge Wang,
Matt Davison,
Kathryn Wang,
Tai-he Xia,
Katherine M. Call,
Jun Luo,
Xingyao Wu,
Riccardo Zuccarino,
Alexa Bacha,
Yunhong Bai,
Laurie Gutmann,
Shawna Feely,
Tiffany Grider,
Alexander M. Rossor,
Michael E. Shy,
John Svaren
Publication year - 2021
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000012266
Subject(s) - peripheral myelin protein 22 , microrna , neurofilament , schwann cell , biomarker , pathogenesis , biology , peripheral neuropathy , pathology , medicine , bioinformatics , genetics , phenotype , gene , immunohistochemistry , endocrinology , diabetes mellitus
To determine whether microRNAs (miRs) are elevated in the plasma of individuals with the inherited peripheral neuropathy Charcot-Marie-Tooth disease type 1A (CMT1A), miR profiling was employed to compare control and CMT1A plasma.