Open AccessWhite Matter Disruption in Pediatric Traumatic Brain Injury
Author(s) -
Emily L. Dennis,
Karen Caeyenberghs,
Kristen R. Hoskinson,
Tricia L. Merkley,
Stacy J. Suskauer,
Robert F. Asarnow,
Talin Babikian,
Brenda Bartnik-Olson,
Kevin Bickart,
Erin D. Bigler,
Linda EwingCobbs,
Anthony Figaji,
Christopher C. Giza,
Naomi J. GoodrichHunsaker,
Cooper B. Hodges,
Elizabeth S Hovenden Aa,
Andrei Irimia,
Marsh Königs,
Harvey S. Levin,
Hannah M. Lindsey,
Jeffrey E. Max,
Mary R. Newsome,
Alexander Olsen,
Nicholas Ryan,
Adam Schmidt,
Matthew S Spruiell,
Benjamin Wade,
Ashley L. Ware,
Christopher G. Watson,
Anne Wheeler,
Keith Owen Yeates,
Brandon A. Zielinski,
Peter Kochunov,
Neda Jahanshad,
Paul M. Thompson,
David F. Tate,
Elisabeth A. Wilde
Publication year - 2021
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000012222
Subject(s) - fractional anisotropy , traumatic brain injury , white matter , neurocognitive , medicine , uncinate fasciculus , diffusion mri , neuroimaging , psychology , magnetic resonance imaging , psychiatry , cognition , radiology
Our study addressed aims: (1) test the hypothesis that moderate-severe TBI in pediatric patients is associated with widespread white matter (WM) disruption; (2) test the hypothesis that age and sex impact WM organization after injury; and (3) examine associations between WM organization and neurobehavioral outcomes.