Open AccessProspective Quantification of CSF Biomarkers in Antibody-Mediated Encephalitis
Author(s) -
Gregory S. Day,
Melanie Y Yarbrough,
Péter Körtvelyessy,
Harald Prüß,
Robert C. Bucelli,
Marvin J. Fritzler,
Warren Mason,
David F. TangWai,
Claude Steriade,
J. Hébert,
Rachel L. Henson,
Elizabeth M. Herries,
Jack H. Ladenson,
A. Sebastian López-Chiriboga,
Neill R. GraffRadford,
John C. Morris,
Anne M. Fagan
Publication year - 2021
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000011937
Subject(s) - neurogranin , snap , medicine , neuroinflammation , biomarker , modified rankin scale , cerebrospinal fluid , encephalitis , receiver operating characteristic , hazard ratio , autoimmune encephalitis , pathology , neuromyelitis optica , confidence interval , gastroenterology , antibody , inflammation , immunology , biology , biochemistry , virus , computer graphics (images) , ischemic stroke , protein kinase c , ischemia , computer science , enzyme
To determine whether neuronal and neuroaxonal injury, neuroinflammation, and synaptic dysfunction associate with clinical course and outcomes in antibody-mediated encephalitis (AME), we measured biomarkers of these processes in CSF from patients presenting with AME and cognitively normal individuals.