Open AccessSlow-Wave Sleep and MRI Markers of Brain Aging in a Community-Based Sample
Author(s) -
AndréeAnn Baril,
Alexa S. Beiser,
Vincent Mysliwiec,
Erlan Sanchez,
Charles DeCarli,
Susan Redline,
Daniel J. Gottlieb,
Pauline Maillard,
José R. Romero,
Claudia L. Satizabal,
Jared M. Zucker,
Sudha Seshadri,
Matthew P. Pase,
Jayandra J. Himali
Publication year - 2021
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000011377
Subject(s) - brain size , medicine , polysomnography , cardiology , hyperintensity , white matter , slow wave sleep , psychology , magnetic resonance imaging , audiology , electroencephalography , radiology , psychiatry , apnea
To test the hypothesis that reduced slow-wave sleep, or N3 sleep, which is thought to underlie the restorative functions of sleep, is associated with MRI markers of brain aging, we evaluated this relationship in the community-based Framingham Heart Study Offspring cohort using polysomnography and brain MRI.