Open AccessProspective Analysis of Leisure-Time Physical Activity in Midlife and Beyond and Brain Damage on MRI in Older Adults
Author(s) -
Priya Palta,
A. Richey Sharrett,
Kelley Pettee Gabriel,
Rebecca F. Gottesman,
Aaron R. Folsom,
Melinda C. Power,
Kelly R. Evenson,
Clifford R. Jack,
David S. Knopman,
Thomas H. Mosley,
Gerardo Heiss
Publication year - 2021
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000011375
Subject(s) - medicine , confidence interval , odds ratio , fractional anisotropy , white matter , logistic regression , hyperintensity , cardiology , demography , magnetic resonance imaging , sociology , radiology
To test the hypothesis that greater levels of leisure-time moderate to vigorous intensity physical activity (MVPA) in midlife or late life are associated with larger gray matter volumes, less white matter disease, and fewer cerebrovascular lesions measured in late life, we utilized data from 1,604 participants enrolled in the Atherosclerosis Risk in Communities study.