Open AccessPhysical activity and risk of Alzheimer disease
Author(s) -
Sebastian E. Baumeister,
André Karch,
Martin Bahls,
Alexander Teumer,
Michael F. Leitzmann,
Hansjörg Baurecht
Publication year - 2020
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000010013
Subject(s) - mendelian randomization , odds ratio , confidence interval , single nucleotide polymorphism , observational study , medicine , disease , population , genome wide association study , alzheimer's disease , demography , genetics , biology , genotype , environmental health , genetic variants , gene , sociology
Evidence from observational studies for the effect of physical activity on the risk of Alzheimer disease (AD) is inconclusive. We performed a 2-sample mendelian randomization analysis to examine whether physical activity is protective for AD.