Open Accessβ-Glucocerebrosidase activity in GBA -linked Parkinson disease
Author(s) -
Young Eun Huh,
Ming Sum R. Chiang,
Joseph J. Locascio,
Zhixiang Liao,
Ganqiang Liu,
Karbi Choudhury,
Yuliya I. Kuras,
Idil Tuncali,
Aleksandar Videnović,
Amelia R. Hunt,
Michael A. Schwarzschild,
Albert Y. Hung,
Todd M. Herrington,
Michael T. Hayes,
Bradley T. Hyman,
AnneMarie Wills,
Stephen N. Gomperts,
John H. Growdon,
S. Pablo Sardi,
Clemens R. Scherzer
Publication year - 2020
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000009989
Subject(s) - glucocerebrosidase , interquartile range , medicine , gastroenterology , parkinson's disease , confidence interval , disease
To test the relationship between clinically relevant types of GBA mutations (none, risk variants, mild mutations, severe mutations) and β-glucocerebrosidase activity in patients with Parkinson disease (PD) in cross-sectional and longitudinal case-control studies.