Open AccessNeurofilament light as a biomarker in traumatic brain injury
Author(s) -
Pashtun Shahim,
Adam Politis,
André van der Merwe,
Brian Moore,
YiYu Chou,
Dzung L. Pham,
John A. Butman,
Ramon DiazArrastia,
Jessica Gill,
David L. Brody,
Henrik Zetterberg,
Kaj Blennow,
Leighton Chan
Publication year - 2020
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000009983
Subject(s) - traumatic brain injury , medicine , concussion , cohort , biomarker , receiver operating characteristic , injury severity score , diffusion mri , poison control , magnetic resonance imaging , injury prevention , radiology , emergency medicine , psychiatry , biochemistry , chemistry
To determine whether serum neurofilament light (NfL) correlates with CSF NfL, traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor imaging (DTI) estimates of traumatic axonal injury (TAI).