Open AccessDifferent phenotypes in dermatomyositis associated with anti-MDA5 antibody
Author(s) -
Yves Allenbach,
Y. Uzunhan,
S. Toquet,
Gaëlle Leroux,
Laure Gallay,
A. Marquet,
Alain Meyer,
Constance Guillaud,
Nicolas Limal,
Frédéric Gagnadoux,
Baptiste Hervier,
R. Borie,
C. Deligny,
Benjamin Terrier,
Alice Berezné,
Sylvain Audia,
Nicolas Champtiaux,
H. Devilliers,
Nicol C. Voermans,
Elizabeth Diot,
Amélie Servettaz,
Thierry Marhadour,
Vincent Castelain,
S. Humbert,
Claire Blanchard-Delaunay,
N. Tieulié,
Pierre Charles,
M. Gérin,
A. Mékinian,
Pascaline Priou,
J.-C. Meurice,
Abdellatif Tazi,
Vincent Cottin,
Makoto Miyara,
Benjamin Grange,
Dominique IsraëlBiet,
S. Phin-Huynh,
Camille Bron,
Luc de Saint Martin,
Nicole Fabien,
K. Mariampillai,
Hilario Nunès,
Olivier Benveniste
Publication year - 2020
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000009727
Subject(s) - dermatomyositis , medicine , rash , interstitial lung disease , myositis , dermatology , arthritis , antibody , connective tissue disease , gastroenterology , pathology , autoimmune disease , immunology , lung
The predominance of extramuscular manifestations (e.g., skin rash, arthralgia, interstitial lung disease [ILD]) as well as the low frequency of muscle signs in anti-melanoma differentiation-associated gene 5 antibody-positive (anti-MDA5+) dermatomyositis caused us to question the term myositis-specific antibody for the anti-MDA5 antibody, as well as the homogeneity of the disease.