Open AccessThe CLN3 Disease Staging System
Author(s) -
Margaux C. Masten,
Justin D. Williams,
Jennifer Vermilion,
Heather Adams,
Amy Vierhile,
Alyssa Collins,
Frederick J. Marshall,
Erika F. Augustine,
Jonathan W. Mink
Publication year - 2020
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000009454
Subject(s) - disease , natural history study , cohort , rating scale , medicine , stage (stratigraphy) , natural history , clinical trial , staging system , psychology , developmental psychology , biology , paleontology , cancer
To develop a disease-specific staging system for CLN3 disease and to test the hypothesis that salient and discrete clinical features of CLN3 disease may be used to define disease stages by analyzed data from an 18-year-long natural history study.