Open AccessDevelopment and validation of a disease severity index for ataxia of Charlevoix-Saguenay
Author(s) -
Cynthia Gag,
Bernard Brais,
Isabelle Lessard,
Caroline Lavoie,
Isabelle Côté,
Jean Mathieu
Publication year - 2019
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000008313
Subject(s) - cronbach's alpha , construct validity , medicine , rating scale , population , ataxia , psychology , psychometrics , psychiatry , clinical psychology , developmental psychology , environmental health
To develop a disease-specific severity index for adults with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) (DSI-ARSACS) that considers the 3 components (pyramidal, cerebellar, neuropathic) of the disease, and to document its content validity, internal consistency, and construct validity.