Open AccessGanglionic Acetylcholine Receptor Antibodies in Postural Tachycardia Syndrome
Author(s) -
Meredith Bryarly,
Satish R. Raj,
Lauren Phillips,
Linda S. Hynan,
Luis E. Okamoto,
Amy C. Arnold,
Sachin Y. Paranjape,
Megan Vernino,
Bonnie K. Black,
Steven Vernino
Publication year - 2021
Publication title -
neurology. clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 29
eISSN - 2163-0933
pISSN - 2163-0402
DOI - 10.1212/cpj.0000000000001047
Subject(s) - medicine , dysautonomia , antibody , autoantibody , autoimmunity , clinical significance , immunology , endocrinology , disease
Postural tachycardia syndrome (POTS), the most common form of dysautonomia, may be associated with autoimmunity in some cases. Autoantibodies against the ganglionic acetylcholine receptor (gAChR) have been reported in a minority of patients with POTS, but the prevalence and clinical relevance is unclear.