Open AccessSmoking and family history and risk of aneurysmal subarachnoid hemorrhage
Author(s) -
Daniel Woo,
Jane Khoury,
Mary Haverbusch,
Padmini Sekar,
Matthew L. Flaherty,
Dawn Kleindorfer,
Brett M. Kissela,
Charles J. Moomaw,
Ranjan Deka,
Joseph P. Broderick
Publication year - 2009
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/01.wnl.0000338567.90260.46
Subject(s) - subarachnoid hemorrhage , medicine , odds ratio , family history , confidence interval , logistic regression , aneurysm , stroke (engine) , first degree relatives , population , intraventricular hemorrhage , risk factor , cardiology , pediatrics , surgery , pregnancy , gestational age , mechanical engineering , genetics , environmental health , biology , engineering
Smoking and family history of aneurysmal subarachnoid hemorrhage (aSAH) are independent risk factors for aSAH. Using a population-based case-control study of hemorrhagic stroke, we hypothesized that having both a first-degree relative with a brain aneurysm or SAH (+FH) and current smoking interact to increase the risk of aSAH.