Open AccessOR23-5 A Model “Obesogen”, Tributyltin, Promotes Steatosis in Human Liver Cells by Upregulating Lipogenic Gene Expression as a Consequence of Alterations in Both Genomic and Non-Genomic Signaling
Author(s) -
Yue Chen,
Lindsey S. Treviño,
Tiffany A. Katz,
Ross A. Hamilton,
Anna Malovannaya,
Fabio Stossi,
Cristian Coarfa,
Charles E. Foulds
Publication year - 2019
Publication title -
journal of the endocrine society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.046
H-Index - 20
ISSN - 2472-1972
DOI - 10.1210/js.2019-or23-5
Subject(s) - tributyltin , peroxisome proliferator activated receptor , gene knockdown , transcriptome , retinoid x receptor , biology , lipid metabolism , small interfering rna , steatosis , microbiology and biotechnology , lipid droplet , fatty liver , lipogenesis , nuclear receptor , chemistry , gene , transfection , medicine , gene expression , endocrinology , biochemistry , transcription factor , ecology , disease