Body Mass Index and Risk of Alzheimer’s Disease: A Mendelian Randomization Study of 399,536 Individuals
Author(s) -
Liv Tybjærg Nordestgaard,
Anne TybjærgHansen,
Børge G. Nordestgaard,
Ruth FrikkeSchmidt
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-00195
Subject(s) - mendelian randomization , odds ratio , body mass index , hazard ratio , medicine , population , disease , confidence interval , dementia , risk factor , observational study , demography , genetics , biology , genotype , environmental health , sociology , genetic variants , gene
Recently, data on 2,000,000 people established that low body mass index (BMI) is associated with increased risk of dementia. Whether this observational association reflects a causal effect remains to be clarified.
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