Open AccessHypoglycosylated hFSH Has Greater Bioactivity Than Fully Glycosylated Recombinant hFSH in Human Granulosa Cells
Author(s) -
Chao Jiang,
Xiaoying Hou,
Cheng Wang,
Jeffrey V. May,
Viktor Y. Butnev,
George R. Bousfield,
John S. Davis
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-1317
Subject(s) - creb , granulosa cell , medicine , endocrinology , follicle stimulating hormone , phosphorylation , aromatase , stimulation , estrogen , recombinant dna , protein kinase a , biology , hormone , chemistry , transcription factor , microbiology and biotechnology , luteinizing hormone , biochemistry , cancer , breast cancer , gene
Previous studies suggest that aging in women is associated with a reduction in hypoglycosylated forms of FSH.