Open AccessRisk of Neoplasia in Pediatric Patients Receiving Growth Hormone Therapy—A Report From the Pediatric Endocrine Society Drug and Therapeutics Committee
Author(s) -
Sripriya Raman,
Adda Grimberg,
Steven G. Waguespack,
Bradley S. Miller,
Charles A. Sklar,
Lillian R. Meacham,
Briana Patterson
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2015-1002
Subject(s) - endocrine system , medicine , drug , growth hormone , intensive care medicine , hormone , oncology , pediatrics , pharmacology
GH and IGF-1 have been shown to affect tumor growth in vitro and in some animal models. This report summarizes the available evidence on whether GH therapy in childhood is associated with an increased risk of neoplasia during treatment or after treatment is completed.