Open AccessEffect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat
Author(s) -
Jean-Marc Schwarz,
Susan M. Noworolski,
Ming Wen,
Artem Dyachenko,
Jessica L. Prior,
Melissa E. Weinberg,
Laurie A. Herraiz,
Viva Tai,
Nathalie Bergeron,
Thomas P. Bersot,
Madhu N. Rao,
Morris Schambelan,
Kathleen Mulligan
Publication year - 2015
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-3678
Subject(s) - lipogenesis , medicine , endocrinology , fructose , hyperinsulinemia , carbohydrate , fatty liver , chemistry , insulin , weight gain , biology , lipid metabolism , insulin resistance , body weight , biochemistry , disease
Consumption of high-fructose diets promotes hepatic fatty acid synthesis (de novo lipogenesis [DNL]) and an atherogenic lipid profile. It is unclear whether these effects occur independent of positive energy balance and weight gain.