Central QCT Reveals Lower Volumetric BMD and Stiffness in Premenopausal Women with Idiopathic Osteoporosis, Regardless of Fracture History | Zendy

Adi Cohen | Zendy; Thomas Lang | Zendy; Donald J. McMahon | Zendy; X. Sherry Liu | Zendy; X. Edward Guo | Zendy; Chiyuan Zhang | Zendy; Emily M. Stein | Zendy; David W. Dempster | Zendy; Polly Young | Zendy; Isra Saeed | Zendy; Joan M. Lappe | Zendy; Robert R. Recker | Zendy; Elizabeth Shane | Zendy

Open Access

Central QCT Reveals Lower Volumetric BMD and Stiffness in Premenopausal Women with Idiopathic Osteoporosis, Regardless of Fracture History

Author(s) -

Adi Cohen,

Thomas Lang,

Donald J. McMahon,

X. Sherry Liu,

X. Edward Guo,

Chiyuan Zhang,

Emily M. Stein,

David W. Dempster,

Polly Young,

Isra Saeed,

Joan M. Lappe,

Robert R. Recker,

Elizabeth Shane

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2099

Subject(s) - medicine , osteoporosis , bone mineral , femoral neck , quantitative computed tomography , bone density , trabecular bone score , urology

Idiopathic osteoporosis (IOP) affects otherwise healthy young individuals with intact gonadal function and no secondary cause of bone fragility. In premenopausal women with IOP, a low trauma fracture is evidence of impaired bone quality and strength. The extent to which low bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA) reflects low volumetric BMD, bone microstructure, and strength is uncertain in the absence of low trauma fracture.

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