Stimulation of GPR30 Increases Release of EMMPRIN-Containing Microvesicles in Human Uterine Epithelial Cells | Zendy

Lindsey A. Burnett | Zendy; Mallory M. Light | Zendy; P. Mehrotra | Zendy; Romana A. Nowak | Zendy

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Stimulation of GPR30 Increases Release of EMMPRIN-Containing Microvesicles in Human Uterine Epithelial Cells

Author(s) -

Lindsey A. Burnett,

Mallory M. Light,

P. Mehrotra,

Romana A. Nowak

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2098

Subject(s) - microvesicle , microvesicles , gper , stimulation , endocrinology , medicine , basigin , receptor , chemistry , microbiology and biotechnology , biology , estrogen receptor , matrix metalloproteinase , biochemistry , microrna , cancer , breast cancer , gene

Uterine remodeling is highly dependent on the glycosylated transmembrane protein extracellular matrix metalloproteinase (MMP) inducer (EMMPRIN). Previous studies indicate estradiol can increase EMMPRIN expression in uterine cells and promote subsequent induction of MMP production.

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