Melanocortin-4 Receptor Signaling Is Required for Weight Loss after Gastric Bypass Surgery | Zendy

Ida J. Hatoum | Zendy; Nicholas Stylopoulos | Zendy; Amanda M. Vanhoose | Zendy; Kelli L. Boyd | Zendy; Deng Ping Yin | Zendy; Kate L. J. Ellacott | Zendy; Lian Li | Zendy; Kasia Blaszczyk | Zendy; Julia M. Keogh | Zendy; Roger D. Cone | Zendy; I. Sadaf Farooqi | Zendy; Lee M. Kaplan | Zendy

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Melanocortin-4 Receptor Signaling Is Required for Weight Loss after Gastric Bypass Surgery

Author(s) -

Ida J. Hatoum,

Nicholas Stylopoulos,

Amanda M. Vanhoose,

Kelli L. Boyd,

Deng Ping Yin,

Kate L. J. Ellacott,

Lian Li,

Kasia Blaszczyk,

Julia M. Keogh,

Roger D. Cone,

I. Sadaf Farooqi,

Lee M. Kaplan

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-3432

Subject(s) - weight loss , melanocortin , melanocortin 4 receptor , biology , gastric bypass surgery , endocrinology , obesity , food intake , energy homeostasis , medicine , receptor , gastric bypass

Roux-en-Y gastric bypass (RYGB) is one of the most effective long-term therapies for the treatment of severe obesity. Recent evidence indicates that RYGB effects weight loss through multiple physiological mechanisms, including changes in energy expenditure, food intake, food preference, and reward pathways.

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