Genetically Determined Dosage of Follicle-Stimulating Hormone (FSH) Affects Male Reproductive Parameters
Author(s) -
Marina Grigorova,
Margus Punab,
Birutė Žilaitienė,
Juris Ērenpreiss,
Kristo Ausmees,
Valentinas Matulevičius,
И. Л. Царев,
Niels Jørgensen,
Maris Laan
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0632
Subject(s) - endocrinology , medicine , genotype , allele , follicle stimulating hormone , biology , testosterone (patch) , single nucleotide polymorphism , liter , population , hormone , luteinizing hormone , genetics , gene , environmental health
The detailed role of FSH in contributing to male testicular function and fertility has been debated. We have previously identified the association between the T-allele of the FSHB promoter polymorphism (rs10835638; G/T, -211 bp from the mRNA start) and significantly reduced male serum FSH.
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