Nonoxidative Free Fatty Acid Disposal Is Greater in Young Women than Men | Zendy

Christina Koutsari | Zendy; Rita Basu | Zendy; Robert A. Rizza | Zendy; K. Sreekumaran Nair | Zendy; Sundeep Khosla | Zendy; Michael D. Jensen | Zendy

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Nonoxidative Free Fatty Acid Disposal Is Greater in Young Women than Men

Author(s) -

Christina Koutsari,

Rita Basu,

Robert A. Rizza,

K. Sreekumaran Nair,

Sundeep Khosla,

Michael D. Jensen

Publication year - 2010

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2010-1651

Subject(s) - medicine , endocrinology , triglyceride , fatty acid , context (archaeology) , hypertriglyceridemia , insulin , chemistry , biology , cholesterol , biochemistry , paleontology

Large increases in systemic free fatty acid (FFA) availability in the absence of a corresponding increase in fatty acid oxidation can create a host of metabolic abnormalities. These adverse responses are thought to be the result of fatty acids being shunted into hepatic very low-density lipoprotein-triglyceride production and/or intracellular lipid storage and signaling pathways because tissues are forced to increase nonoxidative FFA disposal.

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