Open AccessCurrent Status of Islet Cell Replacement and Regeneration Therapy
Author(s) -
Philippe A. Halban,
Michael S. German,
Steven E. Kahn,
Gordon C. Weir
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-1819
Subject(s) - regeneration (biology) , islet , cell therapy , medicine , regenerative medicine , beta cell , bioinformatics , diabetes mellitus , stem cell therapy , stem cell , transplantation , biology , endocrinology , microbiology and biotechnology
Beta cell mass and function are decreased to varying degrees in both type 1 and type 2 diabetes. In the future, islet cell replacement or regeneration therapy may thus offer therapeutic benefit to people with diabetes, but there are major challenges to be overcome.