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Vascular Endothelial Estrogen Receptor α Is Modulated by Estrogen Status and Related to Endothelial Function and Endothelial Nitric Oxide Synthase in Healthy Women
Author(s) -
Kathleen M. Gavin,
Douglas R. Seals,
Annemarie Silver,
Kerrie L. Moreau
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-0278
Subject(s) - estrogen , endocrinology , medicine , estrogen receptor , vascular endothelial growth factor b , endothelial stem cell , endothelium , endothelial dysfunction , estrogen receptor beta , nitric oxide , context (archaeology) , biology , vascular endothelial growth factor a , vascular endothelial growth factor , biochemistry , vegf receptors , in vitro , cancer , breast cancer , paleontology
Estrogen receptor alpha (ER alpha), a potent transcription factor expressed in vascular endothelial cells, plays a key role in regulating vascular function and health. We determined whether vascular endothelial cell expression of ER alpha is influenced by estrogen status and is related to vascular endothelial function in healthy women.

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