Prognostic Indicators of Changes in Bone Density Measures in Adolescent Girls with Anorexia Nervosa-II | Zendy

Madhusmita Misra | Zendy; Rajani Prabhakaran | Zendy; Karen K. Miller | Zendy; Mark A. Goldstein | Zendy; Diane Mickley | Zendy; Laura Clauss | Zendy; Patrice Lockhart | Zendy; Jennalee Cord | Zendy; David B. Herzog | Zendy; Debra K. Katzman | Zendy; Anne Klibanski | Zendy

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Prognostic Indicators of Changes in Bone Density Measures in Adolescent Girls with Anorexia Nervosa-II

Author(s) -

Madhusmita Misra,

Rajani Prabhakaran,

Karen K. Miller,

Mark A. Goldstein,

Diane Mickley,

Laura Clauss,

Patrice Lockhart,

Jennalee Cord,

David B. Herzog,

Debra K. Katzman,

Anne Klibanski

Publication year - 2007

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-2419

Subject(s) - ghrelin , medicine , endocrinology , leptin , bone mineral , peptide yy , bone remodeling , body mass index , bone density , appetite , hormone , anorectic , bone resorption , lean body mass , osteoporosis , obesity , neuropeptide y receptor , neuropeptide , food intake , receptor , body weight

Adolescents with anorexia nervosa (AN) have low bone mineral density (BMD). Baseline predictors of temporal BMD changes (DeltaBMD) in AN, including 1) gastrointestinal peptides regulating food intake and appetite that have been related to bone metabolism and 2) bone turnover markers, have not been well characterized. We hypothesized that baseline levels of nutritionally regulated hormones and of bone turnover markers would predict DeltaBMD overall.

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