A Polygenic Risk Score to Predict Future Adult Short Stature Among Children | Zendy

Tianyuan Lu | Zendy; Vincenzo Forgetta | Zendy; Haoyu Wu | Zendy; John R. B. Perry | Zendy; Ken K. Ong | Zendy; Celia M.T. Greenwood | Zendy; Nicholas J. Timpson | Zendy; Despoina Manousaki | Zendy; J. Brent Richards | Zendy

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A Polygenic Risk Score to Predict Future Adult Short Stature Among Children

Author(s) -

Tianyuan Lu,

Vincenzo Forgetta,

Haoyu Wu,

John R. B. Perry,

Ken K. Ong,

Celia M.T. Greenwood,

Nicholas J. Timpson,

Despoina Manousaki,

J. Brent Richards

Publication year - 2021

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/clinem/dgab215

Subject(s) - demography , cohort , biobank , medicine , longitudinal study , polygenic risk score , context (archaeology) , population , receiver operating characteristic , cohort study , biology , genetics , single nucleotide polymorphism , genotype , pathology , sociology , gene , paleontology

Adult height is highly heritable, yet no genetic predictor has demonstrated clinical utility compared to mid-parental height.

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