Open AccessCancer-Specific Thresholds Adjust for Whole Exome Sequencing–Based Tumor Mutational Burden Distribution
Author(s) -
Evan Fernandez,
Kenneth Eng,
Shaham Beg,
Himisha Beltran,
Bishoy Faltas,
Juan Miguel Mosquera,
David M. Nanus,
David Pisapia,
Rema Rao,
Brian D. Robinson,
Mark A. Rubin,
Olivier Elemento,
Andrea Sboner,
Manish A. Shah,
Wei Song
Publication year - 2019
Publication title -
jco precision oncology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.405
H-Index - 22
ISSN - 2473-4284
DOI - 10.1200/po.18.00400
Subject(s) - cancer , context (archaeology) , exome sequencing , medicine , oncology , biology , mutation , genetics , gene , paleontology
To understand the clinical context of tumor mutational burden (TMB) when comparing a pan-cancer threshold and a cancer-specific threshold.