Open AccessHarnessing Clinical Sequencing Data for Survival Stratification of Patients With Metastatic Lung Adenocarcinomas
Author(s) -
Ronglai Shen,
Axel Martin,
Ai Ni,
Matthew D. Hellmann,
Kathryn C. Arbour,
Emmet Jordan,
Arshi Arora,
Ryan Ptashkin,
Ahmet Zehir,
Mark G. Kris,
Charles M. Rudin,
Michael F. Berger,
David B. Solit,
Venkatraman Seshan,
Maria E. Arcila,
Marc Ladanyi,
Gregory J. Riely
Publication year - 2019
Publication title -
jco precision oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.405
H-Index - 22
ISSN - 2473-4284
DOI - 10.1200/po.18.00307
Subject(s) - ros1 , medicine , oncology , cohort , hazard ratio , adenocarcinoma , lung cancer , kras , precision medicine , cancer , confidence interval , pathology , colorectal cancer
Broad panel sequencing of tumors facilitates routine care of people with cancer as well as clinical trial matching for novel genome-directed therapies. We sought to extend the use of broad panel sequencing results to survival stratification and clinical outcome prediction.